The CDC recommends that most people get a Pfizer or Moderna COVID-19 vaccine over the Johnson & Johnson vaccine, but there is no preference between the Pfizer or Moderna vaccine. These two vaccines are widely available, and for most people, getting the first available COVID vaccine is the best thing you can do to safeguard your health. If you have additional questions about which vaccine is best for you, check with your doctor.

The Pfizer and Moderna COVID-19 vaccines have both received full FDA approval. Before receiving EUA, all three vaccines underwent rigorous testing and review—including clinical trials with tens of thousands of people, and the FDA evaluated comprehensive data on their safety and effectiveness. All three showed excellent safety and effectiveness profiles, and now, hundreds of millions of vaccine doses in the U.S. and billions worldwide have been safely administered. The Johnson & Johnson vaccines will continue to be safely administered through emergency use authorization as the FDA reviews data about their real-world use. 

February 2, 2021

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