Can I mix and match my COVID-19 vaccine and booster?

Yes. The CDC’s clinical guidance advises people to get the same booster as their initial vaccine, but allows people to mix and match depending on availability or if they have a different preference. Mixing and matching COVID-19 vaccines refers to getting a different COVID-19 booster than the initial vaccine (e.g. getting a Pfizer booster after the Moderna vaccine, or a Moderna booster after the J&J vaccine). People who are eligible can get a booster shot with any available COVID-19 vaccine, regardless of whether they received the J&J, Moderna, or Pfizer vaccine for their initial dose(s). 

If you have questions about your eligibility for booster doses or which booster you should get, speak to your health care provider.

Updated November 22, 2021